Pharmacogenomics Guidelines MCP Server
Find pharmacogenomics guidelines, translate diplotypes, and retrieve prescribing recommendations.
Connect it
Settings → Connectors → Add custom connector
URL: https://pharmacogenomics-guidelines.caseyjhand.com/mcpSettings → Apps & Connectors → Advanced → Developer mode
Create connector with URL: https://pharmacogenomics-guidelines.caseyjhand.com/mcp{
"mcpServers": {
"pharmacogenomics-guidelines-mcp-server": {
"url": "https://pharmacogenomics-guidelines.caseyjhand.com/mcp"
}
}
}claude mcp add --transport http pharmacogenomics-guidelines-mcp-server https://pharmacogenomics-guidelines.caseyjhand.com/mcp{
"servers": {
"pharmacogenomics-guidelines-mcp-server": {
"type": "http",
"url": "https://pharmacogenomics-guidelines.caseyjhand.com/mcp"
}
}
}{
"mcpServers": {
"pharmacogenomics-guidelines-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pharmacogenomics-guidelines-mcp-server@0.2.1"
]
}
}
}claude mcp add pharmacogenomics-guidelines-mcp-server -- npx -y @cyanheads/pharmacogenomics-guidelines-mcp-server@0.2.16 tools, pulled live
pgx_search_pairsread-onlySearch evaluated geneâdrug pairs by gene, literal drug-name substring, exact drug/RxNorm/ATC identifiers, evaluation level or testing label. Filters combine with AND; identifiers never fall back to name-only search. Results include source drug identifiers and guideline links for pgx_get_guideline. A pair evaluation is not a prescribing recommendation. Follow nextOffset to continue.
pgx_get_guidelineread-onlyRetrieve guideline coverage by source ID, exact gene symbol or exact drug name/ID. Default summary pages complete guideline records with exact drugCount/pairCount. view=drugs or pairs requires by=id and pages only that related collection, retaining its guideline descriptor. Ambiguous drug names page candidates for retry with drugId. Follow page.nextOffset; the 24,000-byte soft budget cuts only bet
pgx_lookup_diplotyperead-onlyTranslate a CPIC-supported diplotype or allele-status result for one gene. Supply geneSymbol and exact diplotype notation, including star alleles, named HLA positive/negative statuses, or non-star sequences; use pgx_search_alleles and pgx_list_reference with topic phenotypes to inspect supported values. Exact lookup precedes bounded reverse-order or status aliases. Multiple source rows remain ambi
pgx_get_recommendationsread-onlyBrowse CPIC recommendations in drug mode with one exact drugName or drugId. Match across drugs in results mode with geneResults or geneSymbol plus phenotype/activityScore, or genotype mode with 1â10 uniquely resolved gene/diplotype entries. Both matching modes accept an optional drug. Optional view=test_alerts selects complete example CDS alerts instead of recommendations, without joins; default
pgx_search_allelesread-onlyInspect CPIC allele function, evidence, definition metadata and complete population frequencies for geneSymbol. Name matches literally first, then a matching gene prefix before a star allele may be removed; clinicalFunctionalStatus matches literal text case-insensitively. Discover genes with pgx_list_reference. Definitions are metadata, not variant interpretation. Frequencies are source fractions;
pgx_list_referenceread-onlyInspect gene symbols, gene-specific source results, CPIC levels, ClinPGx testing labels, recommendation classifications and input formats. phenotypes requires geneSymbol and preserves distinct activity-score rows, frequencies and consultation text. Live genes/phenotypes support paging; static topics return their complete vocabulary without upstream requests. Use returned values in subsequent disco
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