Interpro MCP Server
Search InterPro entries, map protein domains and functional sites, and find proteins by domain.
Connect it
Settings → Connectors → Add custom connector
URL: https://interpro.caseyjhand.com/mcpSettings → Apps & Connectors → Advanced → Developer mode
Create connector with URL: https://interpro.caseyjhand.com/mcp{
"mcpServers": {
"interpro-mcp-server": {
"url": "https://interpro.caseyjhand.com/mcp"
}
}
}claude mcp add --transport http interpro-mcp-server https://interpro.caseyjhand.com/mcp{
"servers": {
"interpro-mcp-server": {
"type": "http",
"url": "https://interpro.caseyjhand.com/mcp"
}
}
}{
"mcpServers": {
"interpro-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/interpro-mcp-server@0.1.3"
]
}
}
}claude mcp add interpro-mcp-server -- npx -y @cyanheads/interpro-mcp-server@0.1.36 tools, pulled live
interpro_list_referenceread-onlyList supported InterPro database slugs, entry types, accession routing patterns, common taxon IDs, or current release information.
interpro_search_entriesread-onlySearch InterPro entries or member signatures by text or entry type. GO filters require sourceDatabase interpro; integratedInto selects member signatures for an InterPro accession. Results are cursor-paged; use interpro_get_entry for full metadata.
interpro_get_entryread-onlyRetrieve one InterPro or member-database entry with full metadata by default. Select optional sections while retaining core and unknown metadata, or supply overlapLimit to page whole overlap records in upstream order; offsets are not a snapshot across calls.
interpro_get_clanread-onlyRetrieve a Pfam, CDD, or PIRSF clan/set and a cursor page of member entries; optionally include its relationship graph, returned in slices that fit the response budget and paged with relationshipOffset.
interpro_get_protein_domainsread-onlyRetrieve InterPro and member-signature matches on a canonical UniProt protein, preserving every location and discontinuous fragment. Optionally select records covering a residue, include extra predicted features, and include functional residue rules with provenance. Budgeted segments hold whole records in order: matches, requested extras, then requested residue rules sorted by key. The first segme
interpro_find_proteins_by_domainread-onlyFind UniProt proteins carrying an InterPro or member signature. Defaults to reviewed human proteins; reviewedOnly=false includes all review statuses in the chosen taxon. Optional isFragment filters fragment annotations; false does not prove sequence completeness. architectureId intersects the provider Pfam grouping with these selections, without implying functional equivalence; metadata-only hits
Alternatives in Search & Research
Compare →
Cellarion Wine RegistryA
Public wine registry and guides: search wines, grapes, regions, appellations. No account.
ZMZoom MeetingsOfficialA
Zoom Meetings server for meeting search, recordings, transcripts, summaries, and meeting assets.
Google Trends MCPA
Google Trends: Search, Images, News, Shopping over time, growth metrics. Free key at trendsmcp.ai
FSFrase SEOA
SEO, GEO & AI Visibility — research, write, optimize, publish & monitor content. 121 tools.
CDclassifier.dev docsA
classifier.dev documentation as tools: list, read and search the reference, benchmark and guides.
Fireflies.aiOfficialA
Search and analyze meeting transcripts, summaries, soundbites and analytics from Fireflies.ai