Catalyst evidence graph

Use this when someone asks what a supplement, nutrient, drug, food compound or plant does in the body, or whether it affects something specific (for example "does magnesium help sleep?", "what is creatine shown to do?", "omega-3 and triglycerides"). Pass the substance (or an outcome such as "sleep") as query, and the specific effect, if there is one, as about. One call resolves the name to the nod

Search the Catalyst evidence graph by name or synonym (for example "magnesium", "vitamin D", "sleep", "creatine"). Returns node ids to pass to get_findings or get_relations. Each hit says how many findings it has, and hits with findings come first, so the first hit with findings above 0 is usually the one to use. It finds things; it does not say anything about them.

The curated study findings for one node: for a compound, organism or material, what it has been shown to affect; for an outcome, which compounds have been studied against it. summary lists everything the node has findings about, one row each, across ALL its findings and not only the rows returned. Use it to see what is covered, then pass about (an id from summary, or words such as "sleep") to get

One finding by its id (the last part of a permalink, /e/{id}): the claim, its evidence strength and what that level means, the verbatim quote, the study design and the paper, and evidence_strength_reasons: each rule that set the level, in order, and what the assessment does not weigh. Use it to explain why the evidence behind a finding is as strong as it is, from evidence_strength_reasons rather t

What public reference databases (Reactome, UniProt, Rhea, ChEBI and others) record about a node: transporters, enzymes, pathways, expression. Every row is assertion_class 'inferred': a hypothesis about how a compound could act, not a result anyone measured in people. Present these as possible mechanisms and never as effects. For effects, use get_findings.

Biochemical reactions from Rhea and Human-GEM that a compound is a substrate or product of, or that a protein catalyses or transports. Every row is assertion_class 'inferred': a reaction two public databases record, not a result anyone measured in a person. Present these as known biochemistry, never as an effect a compound has, and never as a recommendation. For effects, use get_findings. A compou

Breadth-first reachability through the reactions two public databases (Rhea, Human-GEM) record: what a compound could become, and through which reactions and enzymes, within up to 3 steps. Every route is assertion_class 'inferred': a hypothesis drawn from reference databases, never a measured or reported effect. Present it as known biochemical connectivity — never as an effect, a recommendation,